To avoid damage caused by rodents, a mechanical block of the animals’ access routes into buildings is the most important preventive measure. Some buildings are especially costly or difficult to protect mechanically, and the TxGuardian system provides a solution, an electric “fence”, which works even when doors or gates have to be left open. The overall goal of the TxGuardian equipment is to effectively prevent rodents from entering buildings without killing or hurting them. The equipment, as tested in a laboratory setting, was very efficient in demotivating rodents from crossing the electric barriers. The electric shocks received by the mice and rats did not cause pain behaviour beyond the immediate pain nor severe pathoanatomic lesions to the animals.